The AAV Expression System is a powerful tool for studying gene function and regulation. It allows for the study of genes in their native environment, without the need for exogenous expression vectors or transgenic animals. With addgene AAV system, you can skip over the costly and time-consuming human testing stage and go straight to animal testing. This saves you time and money.

The AAV Expression System is based on the use of recombinant adeno-associated virus (rAAV) to deliver genes of interest into cells. rAAV is a single-stranded DNA virus that infects both dividing and non-dividing cells and has a broad host range. Once inside the cell, the rAAV genome is delivered to the nucleus where it can be transcribed and translated into protein.

The AAV Expression System has several advantages over other gene delivery systems. First, because rAAV does not require cell division for infection, it can be used to study genes in both dividing and non-dividing cells. Second, the broad host range of rAAV allows for the study of genes in a variety of cell types and tissues. Finally, the AAV Expression System is highly efficient, with transduction rates typically exceeding 90%.

The AAV Expression System has been used to study a wide variety of genes and their functions. Some of the most notable studies include the  identification of the genes responsible for cancer, the study of developmental processes, and the elucidation of the molecular mechanisms underlying disease.